Subject: Canis familiaris, 35 kg

PE012 priming: Yes

Compound: PE012

Objective: Establish PE012's phenotypic range for subject species

Protocol:
50 mL oral dose, 3 hour observation before dissection

Live observation: Dosage without incident, after 7.3 minutes sudden distress with subject scratching their flank furiously, scratching ceases after successfully removing fur from the reachable body surface.
Subject keeps vocalizing distress, voice range audibly shifting as the facial structure rearranges itself to make room for 2 large, curved fangs.
After a brief period of trashing subject falls prone rolled into a ball and stops vocalizing.
IR observation reveals falling core temperatures, equalizing to the ambient temperature 2.1 hours after initial dosing.
Presuming subject expiration automatic retrieval drone enters the observation enclosure and approaches the subject's body.
IR observation detects a sudden increase in core temperature coinciding with the enclosure's opening, after consulting the Chief Investigator retrieval attempt proceeds.
On approach of the retrieval drone subject's body shifts slightly, and at ~1.2 m distance the subject grabs the drone with
its elongated tail and proceeds to attack it, successfully piercing its armor plating in multiple spots.
Drone is rendered inoperable after a series
of targeted strikes against its wheel joints and successfully flipping the drone on its back.
Subject termination using standard HCN insufflation, second retrieval attempt uneventful.

Dissection findings: Cutis easily removed, subcutis replaced by brittle, sharp scales of keratin.
Neurocranium and brain without macroscopic deviation, major restructuring of the snout, the accessory fangs are revealed to be bone spikes growing from the os zygomaticus, connected to swollen salivary glands pocked by local necrotic lesions - samples taken for toxicology.
Lungs and heart without macroscopic deviation, liver loaded with 3-5 mm large cysts, intestines and pancreas with greenish discoloration.
Superfluous kidneys of variable size (3-18 cm) scattered across the mesenterium secreting a mucous liquid without obvious function.